Active Serum


Our most popular product, this fast-acting, long-term, “results-oriented” formula decreases the appearance of fine lines and wrinkles, evens skin tone, and is excellent for acne-prone skin. Touted by physicians as “remarkable” and “phenomenal,” ACTIVE SERUM™ usually produces results within a couple of days. Potent activity will be noted upon application as evidenced by a cool tingling sensation. Excellent for all skin types and for all ages, this powerful botanical serum leaves the skin moist and smooth.

• Reduces the appearance of fine lines and wrinkles
• Diminishes the appearance of hyperpigmentation and acne
• Smoothes and softens
• Helps reduce pore size
• Provides both rapid and long-term results
• Paraben-free

Active Serum

Professionals recommend ACTIVE SERUM

See real results, like these skincare experts

"My favorite iS CLINICAL product is the ACTIVE SERUM. The reason that this is my favorite product is I can feel it working, I can see results, I have clients that continuously come in for the product with results and seeing is believing."
Michelle Sergio
Cirillo Cosmetic Dermatology
"Science meets beauty! ACTIVE SERUM does more for your skin than 3 creams combined. It’s great for clogged pores, mottled pigmentation and uneven texture. Dramatically improve the luster of your skin with this innovative mixture of scientifically proven ingredients.”
Dr. Amy Lewis
Dermatologist, New York, NY
"The ACTIVE SERUM is probably my favorite iS CLINICAL product. I am very much of a retinoid fan... not everybody can handle a retinoid, and ACTIVE SERUM can be handled by almost everybody... it turns cells over faster, skin will be younger, fresher, more vibrant..."
Bonnie Martin
Anushka Cosmedical Spa & Salon
"Amazing! I have seen incredible results on varied skin types. Rapid improvement to oily, acneic, mature, dry, pigmented, and sun damaged skin. ACTIVE SERUM truly brings balance to the skin!"
Dr. Rebecca Tomlinson
Medical Director, Birou Skin Care Consulting
"iS CLINICAL’s ACTIVE SERUM and SUPER SERUM products have dramatically improved the appearance and texture of my patients’ skin."
Dr. Mary Lee Amerian
Santa Monica Laser & Skincare Center

Source of Glycolic Acid
Gently exfoliates the skin for a renewed complexion
Source of Lactic Acid
A natural exfoliant with moisturizing properties
Source of Salicylic Acid
Exfoliates the skin and deep-cleans pores
Inhibit melanin-producing enzymes in order
to visibly diminish hyperpigmentation


How to apply ACTIVE SERUM

We recommend using ACTIVE SERUM in the evening.

For best results, follow these directions.
  • After cleansing, apply 3-5 drops, smoothing over face and neck.
  • This “active” product will produce a slight tingling sensation, which should dissipate within a few minutes.
  • For best results, follow complete iS CLINICAL skincare regime.
For external use only. Avoid contact with eyes. Store in a cool place.

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