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Receive a complimentary Skin Heroes Set ($89 value) with a $195+ purchase — Use code JUNTRIO26 at checkout. Details

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  • Cleansing Complex - iS CLINICAL Cleansing Complex - iS CLINICAL
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    Cleansing Complex

    Regular price $49.00
    Size: 6 fl. oz. e 180 mL
    STEP 1: CLEANSE

    Cleansing Complex

    RESURFACING, CLEARING, DEEP-CLEANSING

    Regular price $27.00 – $49.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Pro - Heal Serum Advance+ - iS CLINICAL Pro - Heal Serum Advance+ - iS CLINICAL
    Best Seller

    Pro-Heal Serum Advance+

    Regular price $177.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Pro-Heal Serum Advance+

    RESTORATIVE, REVITALIZING, POWERFUL ANTIOXIDANT BLEND

    Regular price $104.00 – $177.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Reparative Moisture Emulsion - iS CLINICAL Reparative Moisture Emulsion - iS CLINICAL
    Best Seller

    Reparative Moisture Emulsion

    Regular price $116.00
    Size: Net wt. 1.7oz e 50 g
    STEP 3: HYDRATE

    Reparative Moisture Emulsion

    RESTORING, HYDRATING, SMOOTHING

    Regular price $116.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Active Serum - iS CLINICAL Active Serum - iS CLINICAL
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    Active Serum

    Regular price $155.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Active Serum

    AGE-DEFYING, CLEARING, BRIGHTENING

    Regular price $96.00 – $155.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Hydra - Cool Serum - iS CLINICAL Hydra - Cool Serum - iS CLINICAL
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    Hydra-Cool Serum

    Regular price $108.00
    Size: 1 fl. oz. e 30 mL
    STEP 3: HYDRATE

    Hydra-Cool Serum

    HYDRATING, SOOTHING, CLEARING

    Regular price $70.00 – $108.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Active Peel System - iS CLINICAL Active Peel System - iS CLINICAL
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    Active Peel System

    Regular price $99.00
    Size: 15 Treatment Sets per Box
    STEP 2: TREAT

    Active Peel System

    AGE-DEFYING, EXFOLIATING, REJUVENATING

    Regular price $99.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Youth Eye Complex - iS CLINICAL Youth Eye Complex - iS CLINICAL
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    Youth Eye Complex

    Regular price $125.00
    Size: Net wt. 0.5 oz e 15 g
    STEP 2: TREAT

    Youth Eye Complex

    Hydrating Eye Cream to Reduce the Appearance of Fine Lines & Wrinkles

    Regular price $125.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Daily Dynamic Hydrator - iS CLINICAL Daily Dynamic Hydrator - iS CLINICAL
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    Daily Dynamic Hydrator

    Regular price $135.00
    Size: Net wt. 1.7 oz e 50 g
    STEP 3: HYDRATE

    Daily Dynamic Hydrator

    HYDRATING, DEFENDING, RENEWING

    Regular price $135.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Super Serum Advance+ - iS CLINICAL Super Serum Advance+ - iS CLINICAL
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    Super Serum Advance+

    Regular price $177.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Super Serum Advance+

    RESTORATIVE, SUPER ANTIOXIDANT, REPARATIVE

    Regular price $104.00 – $177.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Eclipse SPF 50+ - iS CLINICAL Eclipse SPF 50+ - iS CLINICAL

    Eclipse SPF 50+

    Regular price $54.00
    Size: Net wt. 3.5 oz. e 100 g
    Tint: Translucent
    STEP 4: PROTECT

    Eclipse SPF 50+

    ULTRA SHEER, BROAD SPECTRUM, SPF 50+

    Regular price $54.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Retinol+ Emulsion 0.3 - iS CLINICAL Retinol+ Emulsion 0.3 - iS CLINICAL
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    Retinol+ Emulsion 0.3

    Regular price $117.00
    Size: Net wt. 1 oz e 30 g
    STEP 2: TREAT

    Retinol+ Emulsion 0.3

    AGE-DEFYING, SMOOTHING, BRIGHTENING

    Regular price $117.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Sheald Recovery Balm - iS CLINICAL Sheald Recovery Balm - iS CLINICAL
    Best Seller

    Sheald Recovery Balm

    Regular price $89.00
    Size: Net wt. 2 oz. 60 g
    STEP 2: TREAT

    Sheald Recovery Balm

    PROTECTIVE, SOOTHING, NOURISHING

    Regular price $34.00 – $89.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Moisturizing Complex - iS CLINICAL Moisturizing Complex - iS CLINICAL
    Best Seller

    Moisturizing Complex

    Regular price $106.00
    Size: Net wt. 1.7oz e 50 g
    STEP 3: HYDRATE

    Moisturizing Complex

    HYDRATING, SOOTHING, PROTECTING

    Regular price $106.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Warming Honey Cleanser - iS CLINICAL Warming Honey Cleanser - iS CLINICAL

    Warming Honey Cleanser

    Regular price $52.00
    Size: 4 fl. oz. e 120 mL
    STEP 1: CLEANSE

    Warming Honey Cleanser

    DEEP-CLEANSING, MOISTURIZING, SOOTHING

    Regular price $52.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Youth Intensive Crème - iS CLINICAL Youth Intensive Crème - iS CLINICAL

    Youth Intensive Crème

    Regular price $256.00
    Size: Net wt. 1.7 oz. e 50 g
    STEP 2: TREAT

    Youth Intensive Crème

    AGE-DEFYING, HYDRATING, FIRMING

    Regular price $256.00 – $420.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Cleansing Complex Polish - iS CLINICAL Cleansing Complex Polish - iS CLINICAL
    Best Seller

    Cleansing Complex Polish

    Regular price $52.00
    Size: Net wt. 4 oz. e 120 g
    STEP 1: CLEANSE

    Cleansing Complex Polish

    DEEP-CLEANSING, RESURFACING, SMOOTHING

    Regular price $52.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

iS Clinical products represent the intersection of pharmaceutical-grade science and luxury skincare — delivering clinically proven formulations trusted by professionals in 120+ countries. This complete collection brings together the full range of cleansers, treatment serums, moisturizers, sun protection, and specialty products within the Cleanse, Treat, Hydrate, Protect regimen.

Start with the Cleanse step, where Cleansing Complex prepares the skin for optimal absorption of treatment actives. Move to the Treat step with targeted serums like Active Serum and Pro-Heal Serum Advance+ to address specific complexion concerns. The Hydrate step seals in moisture with products like Reparative Moisture Emulsion, and the Protect step completes the regimen with Eclipse SPF 50+ for daily sun defense.

Beyond the core regimen, explore specialty categories including eye care, body treatments, and exfoliants for comprehensive results from head to toe. Every iS Clinical formulation is developed with botanically derived actives and backed by clinical research.

Find your ideal protocol with the skincare recommendation quiz, or explore our best sellers to discover the products professionals recommend most.