NEW

SET THE TONE TO MAXIMIZE YOUR SKINCARE

iS CANCER CARE

JOIN US IN THE FIGHT AGAINST BREAST CANCER

This October, 100% of profits from Poly-Vitamin Serum sales will be donated to the National Breast Cancer Coalition, an organization committed to ending breast cancer through action and advocacy. Learn More

LIMITED-EDITION HOLIDAY SETS

ALL THAT GLOWS

Unwrap the gift of glowing skin with must-have skincare sets that bring radiance to every regimen.

HOLIDAY GIFT GUIDE 2026

GIVE THE GIFT OF HEALTHY-LOOKING SKIN

Discover scientifically advanced skincare and thoughtfully curated gifts for everyone on your list.

Cleansers

Toners & Mists

clinical serum

Serums

Moisturizers

Sunscreens

Eye Care

Exfoliants & Peels

Cream Cleanser - iS CLINICAL Cream Cleanser - iS CLINICAL

Cream Cleanser

Regular price $52.00
Size: 4 fl. oz. e 120 mL
STEP 1: CLEANSE

Cream Cleanser

DEEP-CLEANSING, MOISTURIZING, SOOTHING

Regular price $52.00
Cleansing Complex - iS CLINICAL Cleansing Complex - iS CLINICAL
Award Winner

Cleansing Complex

Regular price $49.00
Size: 6 fl. oz. e 180 mL
STEP 1: CLEANSE

Cleansing Complex

RESURFACING, CLEARING, DEEP-CLEANSING

Regular price $27.00 – $49.00
Daily Active Smoothing Toner - iS CLINICAL Daily Active Smoothing Toner - iS CLINICAL
New

Daily Active Smoothing Toner

Regular price $52.00
Size: 6 fl. oz. e 180 mL
STEP 1: TONE

Daily Active Smoothing Toner

Multi-Acid Exfoliating Toner for Smooth, Balanced, Glowing Skin

Regular price $52.00

POWERED BY OUR EXCLUSIVE GeneXC TECHNOLOGY

EXPECT MORE FROM EVERY DROP

HYDRATE, DEFEND, and RENEW IN ONE INNOVATIVE SOLUTION

LIMITED EDITION

The Active Collection

3 award-winning clinical formulas for a clear complexion
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DISCOVER YOUR ROUTINE

AI Skin Quiz

A customized skincare routine in minutes
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NEW

GeneXC Firming Eye Gel

Firming eye gel with Vitamin C & Peptides
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Professional Treatments

Fire & Ice Facial

Experience the resurfacing and rejuvenation of the award-winning Fire & Ice facial

Exfoliating Clear Skin Facial

Reveal smoother, clearer skin with Exfoliating Clear Skin Facial that deeply cleanses, hydrates, and targets oily or blemish-prone skin

Honey Enzyme Facial

Revitalize the skin with Honey Enzyme Facial, a gentle yet effective treatment that exfoliates, hydrates, and leaves all skin types smoother, brighter, and glowing

Foaming Enzyme Facial

Experience Foaming Enzyme Treatment Facial, a gentle yet powerful exfoliating treatment with fruit enzymes and glycolic acid that leaves all skin types clear, smooth and radiant

Prodigy Peel Systems

Reveal a radiant, revitalized complexion with Prodigy Peel Systems, designed to target mild acne, signs of aging, uneven skin tone, and fine lines

Flash Brightening Peel

Introducing iS Clinical's newest 30- and 60-minute peel treatments that smooth and brighten for a glass-skin look — with zero downtime.