EXCLUSIVE GIFT WITH PURCHASE

Receive a complimentary Super Serum ADVANCE+® ($104 value) with your $225+ purchase*. Use code OCTGIFT26 at checkout.

NEW

SET THE TONE TO MAXIMIZE YOUR SKINCARE

Healthy, glowing skin starts with the first step that resurfaces, hydrates and soothes to make the most of your daily skincare routine.

iS CANCER CARE

JOIN US IN THE FIGHT AGAINST BREAST CANCER

This October, 100% of profits from Poly-Vitamin Serum sales will be donated to the National Breast Cancer Coalition, an organization committed to ending breast cancer through action and advocacy. Learn More

LIMITED-EDITION HOLIDAY SETS

ALL THAT GLOWS

Unwrap the gift of glowing skin with must-have skincare sets that bring radiance to every regimen.

HOLIDAY GIFT GUIDE 2026

GIVE THE GIFT OF HEALTHY-LOOKING SKIN

Discover scientifically advanced skincare and thoughtfully curated gifts for everyone on your list.

Cleansers

Toners & Mists

clinical serum

Serums

Moisturizers

Sunscreens

Eye Care

Exfoliants & Peels

Cream Cleanser - iS CLINICAL Cream Cleanser - iS CLINICAL

Cream Cleanser

Regular price $52.00
Size: 4 fl. oz. e 120 mL
STEP 1: CLEANSE

Cream Cleanser

DEEP-CLEANSING, MOISTURIZING, SOOTHING

Regular price $52.00

GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

Cleansing Complex - iS CLINICAL Cleansing Complex - iS CLINICAL
Award Winner

Cleansing Complex

Regular price $49.00
Size: 6 fl. oz. e 180 mL
STEP 1: CLEANSE

Cleansing Complex

RESURFACING, CLEARING, DEEP-CLEANSING

Regular price $27.00 – $49.00

GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

Daily Active Smoothing Toner - iS CLINICAL Daily Active Smoothing Toner - iS CLINICAL
New

Daily Active Smoothing Toner

Regular price $52.00
Size: 6 fl. oz. e 180 mL
STEP 1: TONE

Daily Active Smoothing Toner

Multi-Acid Exfoliating Toner for Smooth, Balanced, Glowing Skin

Regular price $52.00

GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

POWERED BY OUR EXCLUSIVE GeneXC TECHNOLOGY

EXPECT MORE FROM EVERY DROP

HYDRATE, DEFEND, and RENEW IN ONE INNOVATIVE SOLUTION

LIMITED EDITION

The Active Collection

3 award-winning clinical formulas for a clear complexion
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DISCOVER YOUR ROUTINE

AI Skin Quiz

A customized skincare routine in minutes
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NEW

GeneXC Firming Eye Gel

Firming eye gel with Vitamin C & Peptides
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Professional Treatments

Fire & Ice Facial

Experience the resurfacing and rejuvenation of the award-winning Fire & Ice facial

Exfoliating Clear Skin Facial

Reveal smoother, clearer skin with Exfoliating Clear Skin Facial that deeply cleanses, hydrates, and targets oily or blemish-prone skin

Honey Enzyme Facial

Revitalize the skin with Honey Enzyme Facial, a gentle yet effective treatment that exfoliates, hydrates, and leaves all skin types smoother, brighter, and glowing

Foaming Enzyme Facial

Experience Foaming Enzyme Treatment Facial, a gentle yet powerful exfoliating treatment with fruit enzymes and glycolic acid that leaves all skin types clear, smooth and radiant

Prodigy Peel Systems

Reveal a radiant, revitalized complexion with Prodigy Peel Systems, designed to target mild acne, signs of aging, uneven skin tone, and fine lines

Flash Brightening Peel

Introducing iS Clinical's newest 30- and 60-minute peel treatments that smooth and brighten for a glass-skin look — with zero downtime.