iS Clinical cleansers are formulated with pharmaceutical-grade ingredients to deliver a thorough yet gentle cleanse that prepares skin for the actives that follow. As the essential first step in any professional-grade regimen, each facial cleanser in this collection is designed to remove impurities without stripping the skin's natural moisture barrier.

Cleansing Complex is the collection's cornerstone — a resurfacing cleanser that combines a resurfacing cleanser that combines botanically sourced acids to smooth and clarify skin from the very first step. This professional-grade formula supports the appearance of refined texture and a clearer-looking complexion while maintaining the skin's natural balance. For a more nourishing cleanse, Warming Honey Cleanser delivers a unique warming sensation with honey and vitamin E, providing gentle exfoliation while supporting a softer, more supple-looking complexion.

Cream Cleanser offers a hydrating, non-foaming formula ideal for dry or sensitive skin types — maintaining moisture while effectively removing impurities. For enhanced exfoliation, Cleansing Complex Polish adds eco-friendly microbeads to the original Cleansing Complex formula, delivering a gentle skin-refining cleanser polish that helps smooth and refine skin texture while supporting a more radiant-looking complexion.

Every iS Clinical cleanser reflects the Cleanse step of the Cleanse, Treat, Hydrate, Protect regimen — setting the foundation for optimal absorption of treatment serums and moisturizers that follow. Trusted by skincare professionals in 120+ countries.

Explore the full serums collection to pair with your cleanser, or discover your ideal regimen with the skincare recommendation quiz.