EXCLUSIVE GIFT WITH PURCHASE

EXCLUSIVE GIFT WITH PURCHASE

Receive a complimentary Super Serum ADVANCE+® ($104 Value) with purchases of $225 or more. Use code OCTGIFT26 at checkout. Details

New Arrivals

  • Daily Active Smoothing Toner - iS CLINICAL Daily Active Smoothing Toner - iS CLINICAL
    New

    Daily Active Smoothing Toner

    Regular price $52.00
    Size: 6 fl. oz. e 180 mL
    STEP 1: TONE

    Daily Active Smoothing Toner

    Multi-Acid Exfoliating Toner for Smooth, Balanced, Glowing Skin

    Regular price $52.00

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • Hydrate + Renew Essentials - iS CLINICAL Hydrate + Renew Essentials - iS CLINICAL
    26% Savings

    Hydrate + Renew Essentials

    Regular price $198.00
    (26% Savings)
    Size: Boxed Set

    Hydrate + Renew Essentials

    Holiday set for a renewed glow

    Regular price $198.00
    (26% Savings)

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • Dynamic Glow Must-Haves - iS CLINICAL Dynamic Glow Must-Haves - iS CLINICAL
    27% Savings

    Dynamic Glow Must-Haves

    Regular price $125.00
    (27% Savings)
    Size: Boxed Set

    Dynamic Glow Must-Haves

    Holiday set for luminous, healthy-looking skin

    Regular price $125.00
    (27% Savings)

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • Radiance and Reveal Trio

    Holiday set curated to soothe and revitalize skin

    Regular price $120.00
    (26% Savings)

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • GeneXC Firming Eye Gel - iS CLINICAL GeneXC Firming Eye Gel - iS CLINICAL
    New

    GeneXC Firming Eye Gel

    Regular price $130.00
    STEP 2: TREAT

    GeneXC Firming Eye Gel

    Firming Eye Gel with Vitamin C & Peptides for Fast-Acting Radiance

    Regular price $130.00

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • Extreme Protect SPF 30 - iS CLINICAL Extreme Protect SPF 30 - iS CLINICAL
    Best Seller

    Extreme Protect SPF 30

    Regular price $86.00
    Size: Net wt. 3.5 oz.e 100 g
    STEP 4: PROTECT

    Extreme Protect SPF 30

    HYDRATING, RESTORATIVE, UVA/UVB PROTECTION

    Regular price $53.00 – $86.00

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

  • Daily Dynamic Hydrator - iS CLINICAL
    Award Winner

    Daily Dynamic Hydrator

    Regular price $135.00
    Size: Net wt. 1.7 oz e 50 g
    STEP 3: HYDRATE

    Daily Dynamic Hydrator

    HYDRATING, DEFENDING, RENEWING

    Regular price $52.00 – $135.00

    GIFT WITH PURCHASE: Receive a complimentary Super Serum ADVANCE+® ($104 value) with a $225+ purchase. Use code OCTGIFT26. Details

iS Clinical new arrivals showcase the latest additions to the pharmaceutical-grade skincare portfolio — delivering innovative formulations that reflect ongoing advances in clinical skincare science. Each new product is developed with the same rigorous standards and botanically derived actives that professionals in 60+ countries trust.

New additions to the iS Clinical range are formulated to complement the established Cleanse, Treat, Hydrate, Protect regimen. Whether introducing advanced delivery systems, novel active complexes, or targeted solutions for previously underserved concerns, every launch undergoes extensive testing before joining the collection. Recent innovations build on the brand's legacy of combining scientific efficacy with luxurious textures.

Discover the newest formulations alongside proven favorites. Each product integrates seamlessly with existing iS Clinical regimens, allowing you to enhance your protocol with the latest in professional skincare without disrupting results you already love.

Explore best sellers to see the products professionals recommend most, or find your ideal protocol with the skincare recommendation quiz. Browse by regimen step — Cleanse, Treat, Hydrate, Protect — to see where new products fit within your daily skincare protocol.