EXCLUSIVE GIFT WITH PURCHASE

Receive a complimentary Skin Heroes Set ($89 value) with a $195+ purchase — Use code JUNTRIO26 at checkout. Details

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  • GeneXC Firming Eye Gel - iS CLINICAL GeneXC Firming Eye Gel - iS CLINICAL
    New

    GeneXC Firming Eye Gel

    Regular price $130.00
    STEP 2: TREAT

    GeneXC Firming Eye Gel

    Firming Eye Gel with Vitamin C & Peptides for Fast-Acting Radiance

    Regular price $130.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Extreme Protect SPF 30 - iS CLINICAL Extreme Protect SPF 30 - iS CLINICAL
    Best Seller

    Extreme Protect SPF 30

    Regular price $86.00
    Size: Net wt. 3.5 oz.e 100 g
    STEP 4: PROTECT

    Extreme Protect SPF 30

    HYDRATING, RESTORATIVE, UVA/UVB PROTECTION

    Regular price $53.00 – $86.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • GeneXC Serum - iS CLINICAL GeneXC Serum - iS CLINICAL

    GeneXC Serum

    Regular price $185.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    GeneXC Serum

    PROTECTIVE, RESTORATIVE, AGE-DEFYING

    Regular price $114.00 – $185.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Cream Cleanser - iS CLINICAL Cream Cleanser - iS CLINICAL

    Cream Cleanser

    Regular price $52.00
    Size: 4 fl. oz. e 120 mL
    STEP 1: CLEANSE

    Cream Cleanser

    DEEP-CLEANSING, MOISTURIZING, SOOTHING

    Regular price $52.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • C Eye Serum Advance+ - iS CLINICAL C Eye Serum Advance+ - iS CLINICAL

    C Eye Serum Advance+

    Regular price $75.00
    Size: 15 g e Net wt. 0.5 oz
    STEP 2: TREAT

    C Eye Serum Advance+

    Vitamin C Eye Serum to Brighten & Reduce Visible Signs of Aging

    Regular price $75.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Copper Firming Mist - iS CLINICAL Copper Firming Mist - iS CLINICAL
    Award Winner

    Copper Firming Mist

    Regular price $45.00
    Size: 2.5 fl. oz. e 75 mL
    STEP 2: TREAT

    Copper Firming Mist

    AGE-DEFYING, REFRESHING, FIRMING

    Regular price $45.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Youth Serum - iS CLINICAL Youth Serum - iS CLINICAL

    Youth Serum

    Regular price $174.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Youth Serum

    TIGHTENING, SMOOTHING, RESTORATIVE

    Regular price $174.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Brightening Serum - iS CLINICAL Brightening Serum - iS CLINICAL

    Brightening Serum

    Regular price $152.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Brightening Serum

    TARGETED BRIGHTENING, REVITALIZING, FAST ACTING

    Regular price $90.00 – $152.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Extreme Protect SPF 40 - iS CLINICAL Extreme Protect SPF 40 - iS CLINICAL

    Extreme Protect SPF 40

    Regular price $92.00
    Size: Net wt. 3.5 oz. e 100 g
    Tint: Translucent
    STEP 4: PROTECT

    Extreme Protect SPF 40

    ULTRA SHEER, BROAD SPECTRUM, SPF 50+

    Regular price $92.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Brightening Complex - iS CLINICAL Brightening Complex - iS CLINICAL

    Brightening Complex

    Regular price $166.00
    Size: Net wt. 1 oz. e 30 g
    STEP 2: TREAT

    Brightening Complex

    SAFE BRIGHTENING, HYDRATING, ANTIOXIDANT

    Regular price $166.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Youth Complex - iS CLINICAL Youth Complex - iS CLINICAL

    Youth Complex

    Regular price $172.00
    Size: Net wt. 1 oz. e 30 g
    STEP 2: TREAT

    Youth Complex

    TONING, AGE-DEFYING, TIGHTENING

    Regular price $172.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • NeckPerfect Complex - iS CLINICAL NeckPerfect Complex - iS CLINICAL
    Award Winner

    NeckPerfect Complex

    Regular price $120.00
    Size: Net wt. 1.7 oz. e 50 g
    STEP 2: TREAT

    NeckPerfect Complex

    TIGHTENING, SCULPTING, SMOOTHING

    Regular price $120.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Eye Complex - iS CLINICAL Eye Complex - iS CLINICAL

    Eye Complex

    Regular price $98.00
    Size: Net wt. 0.5 oz e 15 g
    STEP 2: TREAT

    Eye Complex

    Smoothing Eye Cream to Reduce the Look of Puffiness & Dark Circles

    Regular price $98.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • LIProtect SPF 35 - iS CLINICAL LIProtect SPF 35 - iS CLINICAL

    LIProtect SPF 35

    Regular price $25.00
    Size: Net wt. 0.17oz e 5 g
    STEP 4: PROTECT

    LIProtect SPF 35

    PROTECTIVE, NOURISHING, CONDITIONING

    Regular price $25.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • Tri - Active Exfoliating Masque - iS CLINICAL Tri - Active Exfoliating Masque - iS CLINICAL

    Tri-Active Exfoliating Masque

    Regular price $104.00
    Size: Net wt. 4 oz. e 120 g
    STEP 2: TREAT

    Tri-Active Exfoliating Masque

    AGE-DEFYING, RESURFACING, SMOOTHING

    Regular price $104.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26
  • The Active Collection - iS CLINICAL The Active Collection - iS CLINICAL
    29% Savings

    The Active Collection

    Regular price $98.00
    (29% Savings)
    Size: Boxed Set

    The Active Collection

    Regular price $98.00
    (29% Savings)

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • DISCOVER NOW

  • Father's Day Gift Guide

    Give Dad the gift of great skin this Father’s Day with a curated selection of iS Clinical favorites

    DISCOVER NOW

iS Clinical products represent the intersection of pharmaceutical-grade science and luxury skincare — delivering clinically proven formulations trusted by professionals in 120+ countries. This complete collection brings together the full range of cleansers, treatment serums, moisturizers, sun protection, and specialty products within the Cleanse, Treat, Hydrate, Protect regimen.

Start with the Cleanse step, where Cleansing Complex prepares the skin for optimal absorption of treatment actives. Move to the Treat step with targeted serums like Active Serum and Pro-Heal Serum Advance+ to address specific complexion concerns. The Hydrate step seals in moisture with products like Reparative Moisture Emulsion, and the Protect step completes the regimen with Eclipse SPF 50+ for daily sun defense.

Beyond the core regimen, explore specialty categories including eye care, body treatments, and exfoliants for comprehensive results from head to toe. Every iS Clinical formulation is developed with botanically derived actives and backed by clinical research.

Find your ideal protocol with the skincare recommendation quiz, or explore our best sellers to discover the products professionals recommend most.