EXCLUSIVE GIFT WITH PURCHASE

Receive a complimentary Skin Heroes Set ($89 value) with a $195+ purchase — Use code JUNTRIO26 at checkout. Details

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  • Smoothing Essentials Holiday Kit - iS CLINICAL Smoothing Essentials Holiday Kit - iS CLINICAL
    26% Savings

    Smoothing Essentials Holiday Kit

    Regular price $215.00

    Smoothing Essentials Holiday Kit

    Regular price $215.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Pure Radiance Collection - iS CLINICAL Pure Radiance Collection - iS CLINICAL
    24% Savings

    Pure Radiance Collection

    Regular price $278.00
    (24% Savings)
    Size: Boxed Set

    Pure Radiance Collection

    Regular price $278.00
    (24% Savings)

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Extra Strength Active Peel Brightening System - iS CLINICAL Extra Strength Active Peel Brightening System - iS CLINICAL
    Award Winner

    Extra Strength Active Peel Brightening System

    Regular price $120.00
    Size: 15 Treatment Sets per Box
    STEP 2: TREAT

    Extra Strength Active Peel Brightening System

    Regular price $120.00

    Free Skin Heroes Set ($89 value) on orders $195+ — use code JUNTRIO26

  • Father's Day Gift Guide

    Give Dad the gift of great skin this Father’s Day with a curated selection of iS Clinical favorites

    DISCOVER NOW

iS Clinical products represent the intersection of pharmaceutical-grade science and luxury skincare — delivering clinically proven formulations trusted by professionals in 120+ countries. This complete collection brings together the full range of cleansers, treatment serums, moisturizers, sun protection, and specialty products within the Cleanse, Treat, Hydrate, Protect regimen.

Start with the Cleanse step, where Cleansing Complex prepares the skin for optimal absorption of treatment actives. Move to the Treat step with targeted serums like Active Serum and Pro-Heal Serum Advance+ to address specific complexion concerns. The Hydrate step seals in moisture with products like Reparative Moisture Emulsion, and the Protect step completes the regimen with Eclipse SPF 50+ for daily sun defense.

Beyond the core regimen, explore specialty categories including eye care, body treatments, and exfoliants for comprehensive results from head to toe. Every iS Clinical formulation is developed with botanically derived actives and backed by clinical research.

Find your ideal protocol with the skincare recommendation quiz, or explore our best sellers to discover the products professionals recommend most.